Organic acids and derivatives
![Medchemexpress LLC Methyl 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate | 544450-68-2 | 99.9% | C16H16ClNO3S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260202.png-250.jpg)
Medchemexpress LLC Methyl 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate | 544450-68-2 | 99.9% | C16H16ClNO3S | 10MG
COR659 (methyl 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate; CAS 544450-68-2) is a small-molecule positive allosteric modulator of the GABAB receptor used in preclinical neuroscience and addiction research. It has been reported to reduce alcohol- and chocolate-seeking behavior in rodent models and is supplied as a high-purity research chemical for in vitro and in vivo pharmacology studies.
- Potent GABAB positive allosteric modulator with demonstrated in vivo activity.
- High purity suitable for research applications.
- Well characterized chemical identifiers and molecular formula.
- Off-white solid form compatible with standard solvents such as DMSO.
- Storage and handling guidance provided for refrigerated and cryogenic conditions.
Medchemexpress LLC Iacs-8803 diammonium | 00-00-0 | 98.8% | 726.60 g/mol | C20H29FN12O9P2S2 | 5 MG
IACS-8803 diammonium is a potent cyclic dinucleotide STING agonist for preclinical research that activates the STING pathway and has demonstrated systemic antitumor efficacy. The diammonium salt form improves stability for handling and experimental use and is supplied with supporting analytical and safety documentation for research workflows.
- High purity suitable for research use (98.8%).
- Potent STING agonist activity for immuno-oncology studies.
- Suitable for both in vitro and in vivo preclinical experiments.
- Provided with SDS, COA, HNMR, LCMS, and analytical reports.
- Available in multiple small research pack sizes for dose-ranging studies.
Medchemexpress LLC Clomiphene citrate | 50-41-9 | 98.2% | 1 ML
Clomiphene citrate is an orally active estrogen-receptor modulator. It has anti-cancer activity, induces perturbations during meiotic maturation and cytogenetic abnormalities, and aids in managing psychiatric and cognitive impairment.
- Inhibits viability of PC3 human prostate cancer cells
- Induces chromosome abnormalities in mouse oocytes
- Demonstrates anxiolytic potential
- Improves cognitive functions in letrozole-induced polycystic ovary syndrome (PCOS) rats
- Raises NRF-2 gene expression
- Down-regulates acetylcholine esterase expression
Crescent Chemical Co Inc TRIS-(2-CARBOXYETHYL)PHOSPHINE
Tris-(2-carboxyethyl)phosphine hydrochloride Water-soluble and odorless reagent for selective and fast reduction of disulfides. Does not react with other functional groups of proteins. Unreactive towards many common alkylating reagents, so reductions have been carried out simultaneously wit
Selleck Chemical LLC Tamoxifen Citrate S1972-250mg
Tamoxifen Citrate is a selective estrogen receptor modulator (SERM) Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity Tamoxifen induces apoptosis and autophagy
eMolecules 189178-09-4 | Ambeed | Tris(4-ethynylphenyl)amine | 250mg | 624121628 | A693154 | MFCD09030768 | 317.391 | C24H15N
ChemScene | 4-Methyl-3-(methylsulfonyl)aniline | 100mg | 712840109 | CS-0434875 | 307989-41-9 | MFCD16809481 | 185.240 | C8H11NO2S
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Medchemexpress LLC Adenosine 5'-(α,β-methylene)diphosphate triammonium | 99.9% | 476.32 | 1 ML
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. It can be used for the research of the ATP-adenosine pathway. It inhibits 5'-AMP induced adenosine formation in A498 cells at concentrations of 20 and 100 μmol/L.
- CD73 inhibitor
- Used for research of ATP-adenosine pathway
Medchemexpress LLC HO-PEG-CH2COOH | 10000 | HO-(CH2CH2O)n-CH2COOH | 500 MG
HO-PEG-CH2COOH (MW 10,000) is a polyethylene glycol (PEG) polymer terminated with a hydroxyl group and a terminal carboxylic acid. The manufacturer describes it as suitable for use as a PROTAC linker in the synthesis of PROTAC molecules and supplies product documentation including a data sheet and SDS.
Alkali Scientific Citric Acid, Monohydrate, (ACS Grade), 500 G
Citric Acid Monohydrate (ACS Grade, 500 G) is a high-purity reagent used in laboratory procedures that require precise pH control. Its ACS-grade quality makes it suitable for pharmaceutical, biochemical, and chemical applications. Citric Acid is commonly used in buffer preparation, pH adjustment, and as a precursor in the synthesis of other compounds. The 500 G packaging is ideal for smaller laboratories or research projects where a reliable and cost-effective source of citric acid is needed. This monohydrate form offers greater stability compared to anhydrous forms, making it an excellent choice for lab-based experiments and chemical processes.
Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanedioic acid, 1-(1,1-dimethylethyl) ester | 462100-06-7 | ≥97.0% | 307.34 | 250 MG
Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTAC. PROTACs (Proteolysis Targeting Chimeras) consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Suitable for PROTAC synthesis
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC (Z)-aconitic acid | 585-84-2 | MFCD00063184 | 99.3% | 174.11 g/mol | C6H6O6 | 5 MG
(Z)-aconitic acid is a small-molecule endogenous metabolite (cis-aconitic acid) reported to act as a glutamate decarboxylase inhibitor with activity that includes reduction of IκB-α phosphorylation and inhibition of inflammatory responses; supplied as a solid for research use.
- Molecular formula C6H6O6 and molecular weight 174.11 g/mol.
- High reported purity (99.28%).
- Reported activity as a glutamate decarboxylase inhibitor and modulator of IκB-α phosphorylation.
- Applicable to research on inflammatory and metabolic pathways.
- Powder stability: -20°C for long-term storage; defined solvent storage conditions available.
Medchemexpress LLC Sodium citrate monobasic | 18996-35-5 | 98.0% | 214.11 | 500 G
Sodium citrate monobasic is a natural preservative and food tartness enhancer. It induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. It can cause oxidative damage of the liver by decreasing antioxidative enzyme activities. It is also an acidulant, emulsifier, sequestrant, and buffering agent used across many industries.
- Solid appearance
- White to off-white color
- Store at room temperature, keep dry and cool
- In solvent, store at -80°C for 1 year or -20°C for 6 months
Medchemexpress LLC Dicresulene diammoni 50mg | 50MG
Dicresulene diammonium is an impurity of Policresulen an organic acid with hemostatic antimicrobial and antiviral activities[1 [2
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.2% | 10 G
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound also functions as a PEG-based PROTAC linker for the synthesis of PROTACs, which exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Cleavable ADC linker
- PEG-based PROTAC linker
- Used in the synthesis of antibody-drug conjugates
- Used in the synthesis of PROTACs
- Molecular formula: C29H39NO10
- Molecular weight: 561.62
- Soluble in DMSO at 100 mg/mL (178.06 mM); requires ultrasonic
Medchemexpress LLC ζ-Stat trisodium | 31894-34-5 | 97.0% | 450.31 g/mol | C10H5Na3O10S3 | 5MG
ζ-Stat trisodium (trisodium;8-hydroxynaphthalene-1,3,6-trisulfonate) is the trisodium salt of NSC37044 and a selective inhibitor of atypical protein kinase C zeta (PKC-ζ). It is provided as a light yellow to light brown solid for biochemical and cellular research and has been reported to reduce melanoma cell proliferation and induce apoptosis in vitro.